NameEstradiolSynonyms1,3,5-Estratriene-3,17beta-diol; 17beta-Estradiol; 3,17beta-Dihydroxy-1,3,5(10)-estratriene; DihydrofolliculinMolecular StructureMolecular FormulaC18H24O2Molecular Weight272.38CAS Registry Number50-28-2EINECS200-023-8PropertiesMelting point173 ºC Estradiol (E2 or 17β-estradiol) (also oestradiol) is a sex hormone. Estradiol is the predominant sex hormone present in females. It is also present in males, and at a higher level because it is being constantly produced. In females it is only produced 3 out of 30 days of the cycle. It represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.